Contacts lens problem? Help help! Urgent!

Hi.
My eyes feel dry and irritated often?

I tried using biomedics 55 and softlens 66. The dry and irritate eyes get back after a few days even changing a new pair.

I wanted to try Acuvue Oasys with HYDRACLEAR™ PLUS, but its way over my budget!

Is Acuvue Clear good for me?

Please can anyone help me! Please!

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My glasses prescription is slightly messed up?

I ordered my glasses online, and mixed up the Cylinder (astigmatism) with right and left.

My right eye has -4.25 sphere and -.25 cylinder
My left eye has -3.75 and -.5 cylinder, however, i got the cylinder mixed up for the two lens (so left has -.25 and right has -.5). Will this affect my vision strongly in any way?
Added (1). But it's only a 0.25 difference, is it really that bad?

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How to stop red indentations from forming on sides of nose from glasses?

I have tried changing the type of nose piece, added sticky foam pieces (that don't work). I am on the verge of trying plastic glasses with no added nose piece. Any ideas appreciated.

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Will wearing regular sphere contacts harm my astigmatism?

I have astigmatism in one eye and i want to get cosmetic contacts. Is it fine to get them if they are not specifically made for astigmatism? Will it hurt my eye?

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How to weaken my eyesight?

I have one eye that is better than the other, so I always end up buying two boxes of contact lenses and use the left lens from one box and the right from the other, this can be very expensive. Is there's a way in which I can reduce my eyesight in my good eye?

Read more: How to weaken my eyesight?